QLS Seminar - Friday, 22 January at 16:00 (CET)

[ICTP/qls - Valassi Barbara]

Dear All,

on Friday, 22 January 2021 at 16:00 CET, Jonathan E. Dawson, University 
of Rostock, Rostock, Germany, will give a webinar titled:

Dynamical processes in cells and tissues


Abstract: I will present two examples of dynamics and self-organization 
in living systems. Differentiation of adult stem cells into specialised 
cells plays a very important role in tissue regeneration and wound 
healing. Bone healing is a highly complex and tightly regulated 
physiological process that involves proliferation of human mesenchymal 
stem cells and osteogenic differentiation of human mesenchymal stem 
cells into osteoblasts (bone cells). In vitro osteoinduction via 
external electric field is a promising approach to build implants for 
bone regeneration. I will present a general mean-field theoretical 
framework that takes into account processes at the scale of a single 
cell and describes the dynamics of a stem cell population. The theory is 
tested with in vitro experiments involving electrical stimulation of 
human mesenchymal stem cells. The analysis shows that proliferation rate 
is cell density-dependent and that electric field influences only 
osteogenic differentiation.
At the tissue level, leaf vein morphogenesis and patterning involves 
cell shape changes ,and, is under the regulation of plant growth hormone 
auxin. How auxin coordinates the developmental regulation of leaf vein 
is not well understood. I will present a cell based model that captures 
the interplay between key biochemical processes and cell mechanics and 
describes early stages of mid-vein development in a growing leaf 
primordia. Comparison of the model with experiments shows that the 
formation of early vein patterns may essentially be described in terms 
of auxin biosynthesis, its transport, and growth-dependent mechanical 
feedback from surrounding tissues.


Indico webpage: http://indico.ictp.it/event/9525/

Zoom Meeting ID to attend the online seminar: 475-819-702


Join Zoom Meeting: https://zoom.us/j/475819702




If you haven't registered for previous QLS webinars, please contact 
qls at ictp.it to obtain the PASSWORD for this zoom meeting.

Kind regards,
Barbara Valassi for QLS Section