QLS seminar (L. Aparicio) via Zoom on 23 February at 15.00 CET

QLS QLS at ICTP.IT
Thu Feb 18 08:50:35 CET 2021


Dear All,

on Tuesday, 23 February2021 at 15:00 CET, Luis Aparicio (Columbia 
University), will give a seminartitled:


"Applications of Random Matrix Theory to single-cell biology"

Abstract: Recent advances in single-cell technologies provide a unique 
opportunity to study tumor heterogeneity, which is one of the main 
problems in developing therapies for cancer patients. Associated 
technological and biological problems such as sparsity of the data and 
stochasticity of gene expression provide fundamental challenges for 
rigorous subpopulation identification. Random Matrix Theory (RMT) allows 
to deal with those challenges in a systematic way thanks to the 
universality properties at the eigenvalue and eigenvector levels . 
Synergetic use with machine learning algorithms provides a unique avenue 
to distinguish single-cell heterogeneous subpopulations. I will present 
an introduction to the applications of RMT in single-cell biology and an 
application to construct a cell atlas of the human and mouse prostate 
epithelium.


http://indico.ictp.it/event/9588/ <http://indico.ictp.it/event/9588/>


Zoom Meeting ID to attend the online seminar: 475-819-702

Join Zoom Meeting:https://zoom.us/j/475819702 <https://zoom.us/j/475819702>


If you haven't registered for previous QLS webinars, please contact 
qls at ictp.it <mailto:qls at ictp.it>to obtain the PASSWORD for this zoom 
meeting.

Kind regards,
Barbara Valassi for QLS Section



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