QLS seminar (L. Aparicio) via Zoom on 23 February at 15.00 CET
QLS
QLS at ICTP.IT
Thu Feb 18 08:50:35 CET 2021
Dear All,
on Tuesday, 23 February2021 at 15:00 CET, Luis Aparicio (Columbia
University), will give a seminartitled:
"Applications of Random Matrix Theory to single-cell biology"
Abstract: Recent advances in single-cell technologies provide a unique
opportunity to study tumor heterogeneity, which is one of the main
problems in developing therapies for cancer patients. Associated
technological and biological problems such as sparsity of the data and
stochasticity of gene expression provide fundamental challenges for
rigorous subpopulation identification. Random Matrix Theory (RMT) allows
to deal with those challenges in a systematic way thanks to the
universality properties at the eigenvalue and eigenvector levels .
Synergetic use with machine learning algorithms provides a unique avenue
to distinguish single-cell heterogeneous subpopulations. I will present
an introduction to the applications of RMT in single-cell biology and an
application to construct a cell atlas of the human and mouse prostate
epithelium.
http://indico.ictp.it/event/9588/ <http://indico.ictp.it/event/9588/>
Zoom Meeting ID to attend the online seminar: 475-819-702
Join Zoom Meeting:https://zoom.us/j/475819702 <https://zoom.us/j/475819702>
If you haven't registered for previous QLS webinars, please contact
qls at ictp.it <mailto:qls at ictp.it>to obtain the PASSWORD for this zoom
meeting.
Kind regards,
Barbara Valassi for QLS Section
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