Reminder: CBM seminar: January, Tuesday 15th, 10.30 AM

[Maria Teresa]

Dear All,
you are kindly invited at CBM seminar:



Time Domain Optical Imaging, OPTIX and its applications

Rik van Heijningen - Director European Operations ART, Advanced  
Research Technologies Inc. - The Netherlands

January, Tuesday 15th

10.30 AM

Moderator: Dr. Stefania Biffi - CBM

Conference Room, T1 building

AREA Science Park – Basovizza


In TD optical imaging, short pulses of light, driven by pulsed laser  
diodes, are sent to illuminate the specimen under study; where a  
fluorescent probe is excited and time-of-flight distribution is  
determined, enabling the uncoupling of depth and concentration. In  
addition, a fluorescence lifetime is derived – giving an important  
parameter in the measurement of tissue environment and allowing the  
distinction between different fluorescent sources. Time domain  
technology allows the distinction of two fluorophores at the same  
time by their lifetimes. To identify the probes, you can use the dual  
lifetime fitting feature to visualize the two dyes (e.g. RFP and GFP)  
or apply lifetime gating to find the lifetime of a specific  
fluorophore. TD optical imaging is starting to find its way in both  
wide and targeted applications in cancer, neurological diseases, bone  
and mineral research, reporter gene imaging and pharmokinetics, which  
will be shown through the presentation of results from imaging  
centers of excellence throughout the world. TD optical imaging and  
Optix, the most sensitive optical imaging system available today,  
with its ability to monitor many parameters such as depth,  
concentration and lifetime of a fluorescence probe, have the  
capability to provide a crucial milestone in scientific progress, and  
is instrumental in the critical role optical imaging and  
visualization can play in pre-clinical studies.

Some background on the presenter: Rik van Heijningen is the Director  
of European Operations for ART, Advanced Research Technologies, Inc.  
He holds a B.Sc in Biochemistry, from Interstudie, Oss, The  
Netherlands, and a MBA from the University of Birmingham in the UK.  
For the last 15 years he has been active in the commercialization of  
innovative enabling technologies throughout Europe.


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